Clinical Studies

Multiple, peer-reviewed, published studies have shown the effect that Silverlon can have. Studies in a wide variety of Surgical, Wound and Burn Care settings. Explore the studies behind the most advanced, evidence-based antimicrobial dressings available today.

The Use of Silver Nylon in Preventing Surgical Site Infections Following Colon and Rectal Surgery

Authors: Beth Krieger MD, Donald M. Davis MD, Jaime E. Sanchez MD, James J. Mateka, Valentine N. Nfonsam MD, Jared C. Frattini MD, Jorge E. Marcet MD

University of South Florida, Tampa, FL, USA 

Publication: Diseases of the Colon & Rectum (2011)

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surgical

A Clinical Trial to Investigate the Effect of Silver Dressings on Mediastinitis Rates in Postoperative Cardiac Sternotomy Incisions

Authors: Roger Huckfeldt MD FACS, Clyde Redmond MD, Debbie Mikkelson BSM, Phillip J. Finley MS, Cindy Lowe BS CCRP, Jennifer Robertson RN

St John’s Regional Health Center, Springfield, MO, USA

Publication: Ostomy Wound Management (2008)

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surgical

Do Silver-Impregnated Dressings Limit Infections After Lumbar Laminectomy with Instrumented Fusion?

Author: Nancy E. Epstein MD

Albert Einstein College of Medicine, Bronx, NY, USA

Publication: Surgical Neurology (2007) 

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surgical

Left Ventricular Assist Devices: An Innovative Approach to Decrease Infections Using a Silver Contact Dressing

Author: Joan Lerner Selekof BSN RN CWOCN

University of Maryland Medical Center, Baltimore, MD, USA

Presented at Mid Atlantic Region Wound Ostomy and Conference Nurses Annual Conference (2010)

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surgical

CANON: Cardiovascular Surgery Assessment of Silverlon® versus Standard Wound Care Methods

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surgical

Healing Chronic, Ischemic, Infected Saphenous Vein Harvest Sites in the Legs with Silver Plated Cloth and Allograft Dermal Regenerative Matrix

Authors: Stanley Carson MD FACS, Eric Travis DPM, Carol Ajifu PT, DIana To MPT

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surgical

Clinical Case Evaluation and Results of Silverlon® Sternal Dressings in Cardiac Surgery

Author: Brian W. Hummel, M.D., F.A.C.S.

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surgical

Silver Negative Pressure Dressing With Vacuum-assisted Closure of Massive Pelvic and Extremity Wounds

Authors: Herrick J. Siegel MD, Diego F. Herrera MD, Jason Gay CRNFA

University of Alabama at Birmingham (UAB), Birmingham, AL, USA

Publication: Clinical Orthopaedics and Related Research (2013)

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negative-pressure-wound-therapy, wounds

Military Applications of Silver-Nylon Dressings

Author: David J Barillo MD FACS FCCM

Winchester Medical Center, Winchester VA, USA 

Publication: BURNS: The Journal of the International Society of Burn Injuries (2014) 

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military

A Clinical Evaluation of Silverlon® Wound Contact Layer Antimicrobial Wound Dressing

Author: Gareth Owen

Manchester Royal Infirmary, UK

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wounds

Silverlon® use in Afghanistan for Burn Care

Authors: Mary-Margaret Brandt MD, Margaret Tait MT (ASCP), Thomas Toddanio MA MT (ASCP), Wendy Wahl MD

University of Michigan Burn Center, MI, USA

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military, burns

Comparison of Silverlon® Dressing to Xeroform Gauze in the Treatment of Skin Graft Donor Site Wounds

Authors: Michale C. Albrecht MD, Evan Renz MD, Leopoldo C. Cancio MD, Christopher E. White MD, Lorne H. Blackbourne MD, Kevin Chung MD, Eric E. Horvath DO, Peggy Bielke RN, David Baer PhD, Steven E. Wolf MD, John B Holcomb MD

U.S. Army Institute of Surgical Research, Fort Sam Houston, TX, USA

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burns, military

Chronic, Diabetic Foot Wounds with Ischemia and Tissue Loss: Use of Advanced Wound Care Techniques, Silver Plated Cloth, Allografts and Vascular Intervention to Prevent Further Tissue Loss

Authors: Dr. Stanley N. Carson MD FACS, Eric Travis DPM, Diana To MPT

Fountain Valley Regional Hospital, Fountain Valley, CA, USA

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wounds

Treatment of Pyoderma Gangrenosum with a Silver Contact Layer

Author: Dr. Carl Van Gils

Dixie Regional Medical Center Wound Clinic, St. George, UT, USA

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wounds

Do Silver-Based Wound Dressings Reduce Pain?  A Prospective Study and Review of the Literature

Author: Elia Charbel Abboud, Timmothy B. Legare, Judson C. Settle, Amir M. Boubekri, Jorge E. Marcet, and Jaime

Sanchez - University of South Florida, Tampa, Florida, USA and David J Barillo, MD, FACS, FCCM - Mount Pleasant, South Carolina, USA

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surgical

Silverlon® Burn Products Continuum of Burn Care

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burns

Comparison Silverlon® and Acticoat™ Zones of Inhibition

Author: JP Heggers, Journal of Burns

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burns

Use of Pure Metallic Silver – Plated to Nylon Dressing for: Recalcitrant Wounds

Author: Mary Foote, RN MSN ANP CWCN

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wounds

Successful Treatment of a Chronic Venous Ulcer with a Silver Contact Dressing

Author: Carol Publicover MSN, ARNP, CWOCN

Florida Hospital Wound Management Centers

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wounds

Clinical Case Study – Treatment of Coumadin Tissue Necrosis with Silverlon®

Author: Cathy Rogers, APRN, BC, CWCN

SwedishAmerican Hospital Wound Care Clinic

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wounds

An Innovative Approach Using Silver Contact Dressing To Manage Grade IV Skin Lesions

Author: University of Maryland Medical Center

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wounds

Silver Antimicrobial Wound Dressings Cost Comparison

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wounds

Non-Inferiority of a Novel Silver-Plated Dressing for Central Venous Catheters: A Retrospective Cohort Evaluating Rates of Central Line-Associated Bloodstream Infections in Adult Intensive Care Patients

U. of South Florida College of Medicine / Tampa General Hospital

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wounds

Silver Dressings Used With Wound Vacuum Assisted Closure: Is There an Advantage?

Author: Dr. Stanley Carson

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negative-pressure-wound-therapy

Silverlon® NPD Power Point Presentation with Clinical Studies

Author: Argentum Medical, LLC

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negative-pressure-wound-therapy

Healing Skin Grafts over Chronic Wounds with Vacuum Assisted Closure* and Silver Dressings**

Author: Dr. Stanley Carson

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negative-pressure-wound-therapy

Comparison of Healing of Lower Extremity Chronic Wounds with Silver Plated Cloth Dressings, Papain-Urea-Chlorophyllin Ointment and Hydrogel

Author: Dr. Stanley Carson

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negative-pressure-wound-therapy

The Combined Benefit of Negative Pressure Therapy (N.P.T.)

Author: Dr. Stanley Carson

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negative-pressure-wound-therapy

Negative Pressure Therapy Cost Savings Analysis Worksheet

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negative-pressure-wound-therapy

Comparative 7 Day Efficacy Study

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in-vitro

Silver Toxicity and Resistance in Wound Care

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in-vitro

Use of a Silver Nylon Dressing Following Total Hip and Knee Arthroplasty Decreases the Postoperative Infection Rate

Authors: Ashley J. Tisosky MD1, Otatade Iyoha-Bello BSc2, Nicholas Demosthenes BA3, Giovanni Quimbayo MD2, Tara Coreanu BSc4, Ayesha Abdeen MD FRCSC5

Harvard Combined Orthopaedic Residency Program, Massachusetts General Hospital, Boston, MA, USA

Publication: JAAOS - Journal of the American Academy of Orthopaedic Surgeons (2017)

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Silver In Medicine: The Basic Science

Authors: David J Barillo, MD FACS FCCM, David E. Marx DVM

University of Scranton, Scranton, PA, USA

Publication: BURNS: The Journal of International Society of Burn Injuries (2014) 

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Silver in Medicine: A Brief History BC 335 to Present

Authors: David E. Marx DVM, David J Barillo MD FACS FCCM

University of Scranton, Scranton, PA, USA

Publication: BURNS: The Journal of International Society of Burn Injuries (2014) 

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Reduction in Central Line–Associated Bloodstream Infections Correlated With the Introduction of a Novel Silver-Plated Dressing for Central Venous Catheters and Maintained for 6 Years

Authors: Rachel Karlnoski PhD1, Elia Charbel Abboud MD1, Peggy Thompson BSN CIC FAPIC2, Asa Z. Oxner MD3, John T. Sinnott, MD FACP4, Jorge E. Marcet MD FACS FASCRS1

Tampa General Hospital, Tampa, FL, USA 

Publication: Journal of Intensive Care Medicine (2017)

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Please note:

These studies may involve findings that exceed the claims currently cleared by the FDA for the product. Argentum Medical, LLC is not intending to make performance claims about its product. The intent is to disseminate the scientific literature on these products. We encourage you to read these studies to understand the strengths and limitations of the data. For some claims, Argentum is seeking to broaden the indications with the FDA in the future using data, such as these studies, to provide the substantiation.

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