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Clinical Studies

Multiple, peer-reviewed, published studies have shown the effect that Silverlon can have. Studies in a wide variety of Surgical, Wound and Burn Care settings. Explore the studies behind the most advanced, evidence-based antimicrobial dressings available today.

Silverlon: A Weapon Against Driveline Infections in Lvad Patients

Authors:K.R. Barrett,1 B. Ebert,2 and M. Remaly.3

Lehigh Valley Health Network, Allentown, PA; Lehigh Valley Health Network, Harleysville, PA; and the Lehigh Valley Hospital, Germansville, PA.

The Journal of Heart and Lung Transplantation, Vol 42, No 4S, April 2023

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Use of a Silver Nylon Dressing Following Total Hip and Knee Arthroplasty Decreases the Postoperative Infection Rate

Authors: Ashley J. Tisosky MD1, Otatade Iyoha-Bello BSc2, Nicholas Demosthenes BA3, Giovanni Quimbayo MD2, Tara Coreanu BSc4, Ayesha Abdeen MD FRCSC5

Harvard Combined Orthopaedic Residency Program, Massachusetts General Hospital, Boston, MA, USA

Publication: JAAOS - Journal of the American Academy of Orthopaedic Surgeons (2017)

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surgical

The Use of Silver Nylon in Preventing Surgical Site Infections Following Colon and Rectal Surgery

Authors: Beth Krieger MD, Donald M. Davis MD, Jaime E. Sanchez MD, James J. Mateka, Valentine N. Nfonsam MD, Jared C. Frattini MD, Jorge E. Marcet MD

University of South Florida, Tampa, FL, USA 

Publication: Diseases of the Colon & Rectum (2011)

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surgical

Reduction in Central Line–Associated Bloodstream Infections Correlated With the Introduction of a Novel Silver-Plated Dressing for Central Venous Catheters and Maintained for 6 Years

Authors: Rachel Karlnoski PhD1, Elia Charbel Abboud MD1, Peggy Thompson BSN CIC FAPIC2, Asa Z. Oxner MD3, John T. Sinnott, MD FACP4, Jorge E. Marcet MD FACS FASCRS1

Tampa General Hospital, Tampa, FL, USA 

Publication: Journal of Intensive Care Medicine (2017)

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central-line-catheter

A Clinical Trial to Investigate the Effect of Silver Dressings on Mediastinitis Rates in Postoperative Cardiac Sternotomy Incisions

Authors: Roger Huckfeldt MD FACS, Clyde Redmond MD, Debbie Mikkelson BSM, Phillip J. Finley MS, Cindy Lowe BS CCRP, Jennifer Robertson RN

St John’s Regional Health Center, Springfield, MO, USA

Publication: Ostomy Wound Management (2008)

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surgical

Do Silver-Impregnated Dressings Limit Infections After Lumbar Laminectomy with Instrumented Fusion?

Author: Nancy E. Epstein MD

Albert Einstein College of Medicine, Bronx, NY, USA

Publication: Surgical Neurology (2007) 

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surgical

Silver Negative Pressure Dressing With Vacuum-assisted Closure of Massive Pelvic and Extremity Wounds

Authors: Herrick J. Siegel MD, Diego F. Herrera MD, Jason Gay CRNFA

University of Alabama at Birmingham (UAB), Birmingham, AL, USA

Publication: Clinical Orthopaedics and Related Research (2013)

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negative-pressure-wound-therapy, wounds

Military Applications of Silver-Nylon Dressings

Author: David J Barillo MD FACS FCCM

Winchester Medical Center, Winchester VA, USA 

Publication: BURNS: The Journal of the International Society of Burn Injuries (2014) 

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burns-and-military

Silver In Medicine: The Basic Science

Authors: David J Barillo, MD FACS FCCM, David E. Marx DVM

University of Scranton, Scranton, PA, USA

Publication: BURNS: The Journal of International Society of Burn Injuries (2014) 

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surgical, central-line-catheter, wounds, negative-pressure-wound-therapy, burns-and-military, silver-in-medicine

Silver in Medicine: A Brief History BC 335 to Present

Authors: David E. Marx DVM, David J Barillo MD FACS FCCM

University of Scranton, Scranton, PA, USA

Publication: BURNS: The Journal of International Society of Burn Injuries (2014) 

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surgical, central-line-catheter, wounds, negative-pressure-wound-therapy, burns-and-military, silver-in-medicine

A Clinical Evaluation of Silverlon® Wound Contact Layer Antimicrobial Wound Dressing

Author: Gareth Owen

Manchester Royal Infirmary, UK

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wounds

Left Ventricular Assist Devices: An Innovative Approach to Decrease Infections Using a Silver Contact Dressing

Author: Joan Lerner Selekof BSN RN CWOCN

University of Maryland Medical Center, Baltimore, MD, USA

Presented at Mid Atlantic Region Wound Ostomy and Conference Nurses Annual Conference (2010)

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central-line-catheter

Healing Chronic, Ischemic, Infected Saphenous Vein Harvest Sites in the Legs with Silver Plated Cloth and Allograft Dermal Regenerative Matrix

Authors: Stanley Carson MD FACS, Eric Travis DPM, Carol Ajifu PT, DIana To MPT

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surgical

Silver-Based Dressings for the Reduction of Surgical Site Infection: Review of Current Experience and Recommendation for Future Studies

Authors: Elia Charbel Abboud MD, Judson C. Settle MD, Timothy B. Legare MD, Jorge E. Marcet MD, David J. Barillo MD, Jaime E. Sanchez MD


University of South Florida, Tampa, FL, USA

Publication: BURNS: The Journal of the International Society of Burn Injuries

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surgical

Silver-Resistance, Allergy, and Blue Skin: Truth or Urban Legend?

Author: Dr. Jose P. Sterling, MD

St. Vincent Regional Medical Center, Santa Fe, NM, USA

Publication: BURNS: The Journal of the International Society of Burn Injuries (2014)
 

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surgical, central-line-catheter, wounds, negative-pressure-wound-therapy, burns-and-military, silver-in-medicine

Wound Healing and Cost-Saving Benefits of Combining Negative-Pressure Wound Therapy with Silver

Authors: Jeffrey C. Karr DPM, Fernando Loret de Mola MD, Tri Pham MD, Leslie Tooke RN

The Wound Care Center at Lakeland Regional Medical Center, Lakeland, FL, USA

Publication: Advances in Skin & Wound Care (2013)

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negative-pressure-wound-therapy

Utilizing Silver Plated Fabric With Negative Pressure Wound Therapy Poster

Author: Tina Baum, MS, CNS, ACNS-BC, CWON

Florida Hospital North Pinellas

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negative-pressure-wound-therapy

Silverlon® use in Afghanistan for Burn Care

Authors: Mary-Margaret Brandt MD, Margaret Tait MT (ASCP), Thomas Toddanio MA MT (ASCP), Wendy Wahl MD

University of Michigan Burn Center, MI, USA

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burns-and-military

Comparison of Silverlon® Dressing to Xeroform Gauze in the Treatment of Skin Graft Donor Site Wounds

Authors: Michale C. Albrecht MD, Evan Renz MD, Leopoldo C. Cancio MD, Christopher E. White MD, Lorne H. Blackbourne MD, Kevin Chung MD, Eric E. Horvath DO, Peggy Bielke RN, David Baer PhD, Steven E. Wolf MD, John B Holcomb MD

U.S. Army Institute of Surgical Research, Fort Sam Houston, TX, USA

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burns-and-military

A Literature Review of the Military Uses of Silver-Nylon Dressings with Emphasis on Wartime Operations

Author: David J Barillo, MD, FACS, FCCM

Department of Surgery, St. Joseph Mercy Hospital-Ann Arbor, Ann Arbor, MI, USA

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burns-and-military

Chronic, Diabetic Foot Wounds with Ischemia and Tissue Loss: Use of Advanced Wound Care Techniques, Silver Plated Cloth, Allografts and Vascular Intervention to Prevent Further Tissue Loss

Authors: Dr. Stanley N. Carson MD FACS, Eric Travis DPM, Diana To MPT

Fountain Valley Regional Hospital, Fountain Valley, CA, USA

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wounds

Treatment of Pyoderma Gangrenosum with a Silver Contact Layer

Author: Dr. Carl Van Gils

Dixie Regional Medical Center Wound Clinic, St. George, UT, USA

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wounds

The Effect of Blast-Related Burn Injuries from Prolonged Field Care to Rehabilitation and Resilience

Authors: Charles C. Engel, Ryan K. McBain, Samantha McBirney, Sara E. Heins, Molly M. Simmons, Emily Hoch, Mimi Shen, Nicholas Broten, Gulrez Shah Azhar, Tepring Piquado

RAND Corporation

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burns-and-military

Reduce Driveline Trauma Through Stabilization and Exit Site Management: 30 Days Feasibility Results from the Multicenter RESIST Study

Authors: Marcia Stahovich, Kartik S. Sundareswaran, Sarah Fox, William Hallinan, Peggy Blood, Leway Chen, Salpy V. Pamboukian, Raymond Chinn, David J. Farrar, Francis D. Pagani, Laura Blue

ASAIO Journal 2016

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central-line-catheter

Silver-plated Discs at PICC Insertion Sites in the Neonatal ICU

Authors: Gloribel Medina, MHA, MPH, BSN, RNC-NIC, Karen Fugate, MSN, RNC-NIC, CPHQ, Kimberly Atrubin, MPH, CIC, CPHQ, FAPIC

Children's Medical Center, Tampa General Hospital, Tampa, FL, USA

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central-line-catheter

The Use of a Silver-Nylon Dressing During Evacuation of Military Burn Casualties

Authors: Amit Aurora, D.Eng., Alexander Beasy, BA, Julie A. Rizzo, MD, Kevin K. Chung, MD

Original Article

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burns-and-military

Non-Inferiority of a Novel Silver-Plated Dressing for Central Venous Catheters: A retrospective Cohort Evaluating Rates of Central Line-Associated Bloodstream Infections in Adult Intensive Care Patients

Authors: Asa Oxner MD, Andrew Myers MD, John Sinnot MD, FACP, Jorge Marcet MD, Jillian Sajdak, Peggy Thompson BSN, CIC, Charles Myers

University of South Florida College of Medicine

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central-line-catheter

Please note:

These studies may involve findings that exceed the claims currently cleared by the FDA for the product. Argentum Medical, LLC is not intending to make performance claims about its product. The intent is to disseminate the scientific literature on these products. We encourage you to read these studies to understand the strengths and limitations of the data. For some claims, Argentum is seeking to broaden the indications with the FDA in the future using data, such as these studies, to provide the substantiation.

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