Better technology.
Better outcomes.™
Silver Dressing Studies
Advanced Silver Antimicrobial Burn,
Surgical and Wound Care Products
| View: | Wound Dressings | Burn Dressings | Surgical Dressings | Silverlon Home Page |
|
Silver Dressing Studies
|
Advanced Silver Antimicrobial Burn, Surgical and Wound Care Products |
|
|
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
To view the most recent In Vivo Clinical Case Silverlon® Studies, please Click Here
Listed below are 3 categories of Studies for Silverlon® Products. Please click on the category of interest to view the study in which you are interested in. If you would like to view or print the entire study page in a separate Browser Window, please click here |
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
Silverlon®
Antimicrobial Studies
1. USP Antimicrobial Preservative Effectiveness
The USP Antimicrobial Preservative Effectiveness Test determines protection
that Silverlon® fabric provides to microbial contamination. Study was performed by North American
Science Association Inc. Method Duplicate
20 g portions of the test article in 200 ml of saline (SC) were separately
inoculated with the appropriate amount of suspension to achieve an approximate
population of 105 -106 cells per g of test article. Inoculated sample aliquots were held
20-25oC throughout the course of the study. Using various dilution blanks and
Tryptic Soy Agar (TSA) and Sabourauds Dextrose Agar (SDA) for plating,
total plate counts were performed on each sample at 0,7,14,21 and 28
days after inoculation. The
SDA plates were incubated at 20-25oC for 5 days. The TSA plates were incubated at 30-35oC
for 3 days. Results
Interpretation Under the conditions of
this study, Silverlon® was effective in the product examined up to 28
days. 2. Antimicrobial Activity-Dynamic Test of Surfaces
ASTM E 2149
The Antimicrobial Activity-Dynamic Test of Surfaces ASTM E 2149
determines the effectiveness of Silverlon® as a bactericidal antimicrobial. Study was performed by North American Science Association
Inc. Method The antimicrobial activity
of the Silverlon® Wound Contact Dressing 4x4 was evaluated by the Antimicrobial
Activity Dynamic Test of Surfaces ASTM E2149 for 106 CFU/ml
of Pseudomonas aeuroginosa ATCC 9027 and Staphylococcus aureus
(MRSA). Plate counts are performed
at zero time of inoculation and after 1/2 hours, 1 hour, 2 hour and
4 hours of incubation at 370C.
3. Assessment
of Antibacterial Finishes on Textile Materials AATCC Test Method 100
(24 hours)
The Assessment of Antibacterial Finishes on Textile
Materials Method 100 determines whether the antimicrobial agent applied
to a medical device or textile is effective toward inhibiting bacterial
growth. Study was performed by North American Science Association Inc. Method A 4.8 cm disc of Silverlon® is inoculated with 1.2
x 105 CFU of S. aureus and P. aeruginosa. Plate counts are performed at zero
time of inoculation and after 24 hours of incubation at 370C. Test Article:
Silverlon® Test Organism :
Staphylococcus aureus
ATCC 6538
Pseudomonas aeruginosa ATCC 9027 Sample Size:
48 mm diameter disk Pre-Wet Medium:
Sterile Deionized Water Neutralizer:
Letheen Broth Target Inoculum Level:
(1-2) x 105 CFU/0.1
ml Inoculum Concentration:
S. aureus = 1.3 x 105 CFU/0.1 ml
P. aeruginosa = 3.2 x 105 CFU/0.1 ml Test
Date:
5/26/98 Results
Interpretation The antimicrobial agent, silver, applied to the textile
surface was shown to be effective in inhibiting S. aureus and P. aeruginosa 99.93 and 99.97 respectively. 3. Assessment
of Antibacterial Finishes on Textile Materials AATCC Test Method 100
(4 hours)
The Assessment of Antibacterial Finishes on Textile
Materials Method 100 determines whether the antimicrobial agent applied
to a medical device or textile is effective toward inhibiting bacterial
growth. Study was performed by North American Science Association Inc. Method A 4.8 cm disc of Silverlon® is inoculated with 1.2
x 106 CFU of Staphylococcus areus ATCC 6538,
Pseudomonas aeruginosa
ATCC 9027, Enterococcus faecalis (VRE) ATCC 51575
and Staphyloccous aureus
ATCC 33591. Plate
counts are performed at zero time of inoculation and at 30 minutes,
2 hours and 4 hours after incubation at 370C.
Test
Article:
Silverlon® Test Organism:
Staphylococcus areus ATCC 6538 Pseudomonas aeruginosa
ATCC 9027 Enterococcus faecalis (VRE) ATCC 51575
Staphyloccous aureus (MRSA)
ATCC 33591
Sample
Size
48 mm diameter disk Pre-Wet
Medium:
Sterile Deionized Water Neutralizer:
Letheen Broth Target
Inoculum Level:
(1-2) x 106 CFU/
ml Inoculum
Concentration:
(1-2)
x 106 CFU/ml Date: 2/21/02
Assessment of Antimicrobial
Effectiveness Silverlon AATCC Test method 100 Reduction in CFU/ml versus Time Interpretation Interpreting this data in terms of long reduction, the difference between the initial bacterial concentration and the bacterial concentration in CFU/ml at ˝ hour, 2 hours and 4 hours is calculated an summarized in the following table. Assessment of Antimicrobial
Effectiveness Silverlon AATCC Test method 100 Percent Reduction in CFU/ml versus Time
4. Dow Corning Corporate Test Method
0923
The Dow Corning Corporate Test Method determines whether
the antimicrobial agent applied to a medical device or textile is effective
toward inhibiting bacterial growth. Study was performed by North American
Science Association Inc. Method Antimicrobial activity of Silverlon® was evaluated
by shaking a sample in 1.0 – 2.0 c 104 CFU/ml of Staphylococcus
aureus, ATCC 6538 and Pseudomonas
aeruginosa, ATCC 9027 suspensions for one hour contact time. The suspension was diluted before and
after contact to determine bacterial counts. Study was preformed by North
American Science Association Inc. Test Article: Silverlon® Sample Size: 0.75 Target Inoculum Level: (1-2)
x 104 CFU/ml Test Date:
5/26/98 Results
| |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
